• About Us
  • Advertise
  • Contact Us
  • DMCA
  • Follow on Google News
Sunday, May 18, 2025
  • Login
Tribune Newsline
  • Home
  • India
    • National
    • State News
  • Business
  • Education
  • Entertainment
  • Lifestyle
    • Health & Fitness
    • Fashion & Beauty
    • Travel
    • Photography
    • Food
  • Tech
    • App News
    • Gadgets
  • Auto
  • Sports
  • World
  • Others
    • Agriculture
    • Science
    • Astrology
    • Finance/Money
    • Social Work
    • Press Release
    • Religion
No Result
View All Result
  • Home
  • India
    • National
    • State News
  • Business
  • Education
  • Entertainment
  • Lifestyle
    • Health & Fitness
    • Fashion & Beauty
    • Travel
    • Photography
    • Food
  • Tech
    • App News
    • Gadgets
  • Auto
  • Sports
  • World
  • Others
    • Agriculture
    • Science
    • Astrology
    • Finance/Money
    • Social Work
    • Press Release
    • Religion
No Result
View All Result
Tribune Newsline
No Result
View All Result
Home Science

Novel technique may help in early detection of Cancer, Alzheimer’s, and Parkinson’s

Tribune Newsline by Tribune Newsline
February 24, 2021
in Science, Tech
Share on FacebookShare on Twitter

New Delhi: Scientists from Raman Research Institute (RRI) have developed a new technique to measure DNA modifications that can have applications in the early diagnosis of multiple diseases like Cancer, Alzheimer’s, and Parkinson’s diseases.

DNA conformation, in particular, it’s supercoiling, plays an important structural and functional role in gene accessibility as well as in DNA condensation. Alteration in DNA affects their expression and functions. DNA controls cell survival through the genetic code as well as via modifications to its structure. The scientific community was looking for a technique with very high resolution to measure such modifications of DNA structures and observe and understand the molecular mechanisms associated with it to track rare diseases.

Related posts

Upgrade Your Setup this Republic Day with Kingston’s Exclusive Offer!

Upgrade Your Setup this Republic Day with Kingston’s Exclusive Offer!

January 21, 2025
Kingston Technology Remains Top DRAM Module Supplier for 2023

Kingston Technology Remains Top DRAM Module Supplier for 2023

December 8, 2024

The novel nanopore-based platform developed by the scientists can directly measure such modifications or branched DNA properties with the single-molecule resolution even with extremely low amounts of sample. The platform and associated analysis techniques developed by the team can quantitatively assess the distribution of supercoiled branches on DNA plasmids (DNA molecule outside the chromosome).

“Further optimization of the technique can help in the development of portable nano-bio sensors for detection and quantification of protein aggregates and cell-free DNA or nucleosomes. This may help in the early diagnosis of many diseases like Cancer, Alzheimer’s, and Parkinson’s diseases” said Prof GautamVivekSoni, the lead researcher. Currently, researchers at RRI are also exploring applications of this method for virus detection.

The measurement principle of the novel platform is analogous to the Archimedes principle. Individual analyte molecules are driven through a nanopore under an applied voltage, which, during translocation, results in a tiny electrical blip. Charges excluded by the analyte (supercoiled DNA) in the  nanopore are directly proportional to the volume of the particle and are directly measured as the current change. This method utilizes extremely low amounts of sample and can measure DNA structural changes ranging to a few nanometers resolution in the axis perpendicular to the translocation and few tens of nanometers along the translocation axis.

The research team comprise  Dr Sumanth Kumar Maheshwaram, Dr Koushik Sreenivasaa and Prof Gautam Vivek Soni. The research findings have been recently published in the journal ‘Nanoscale’. (India Science Wire)

Tags: DNA Modificationnanoporenew techniqueRRI
Previous Post

‘Crowd and Mask’ Monitoring System to prevent COVID-19

Next Post

Union Minister Dr Jitendra Singh lays the Foundation Stone of new Students’ Hostels in the premises of the famous Cotton University

Tribune Newsline

Tribune Newsline

Related Posts

Upgrade Your Setup this Republic Day with Kingston’s Exclusive Offer!
Tech

Upgrade Your Setup this Republic Day with Kingston’s Exclusive Offer!

January 21, 2025
Kingston Technology Remains Top DRAM Module Supplier for 2023
Tech

Kingston Technology Remains Top DRAM Module Supplier for 2023

December 8, 2024
Kingston’s Best Gifting Options to Strengthen Sibling Bonds This Bhai Dooj
Tech

Kingston’s Best Gifting Options to Strengthen Sibling Bonds This Bhai Dooj

November 4, 2024
Kingston Tech Extravaganza: Amazon Great Indian Sale
Tech

Kingston Tech Extravaganza: Amazon Great Indian Sale

October 10, 2024
Kingston Adds Red Colorway to External SSD Lineup
Tech

Kingston Adds Red Colorway to External SSD Lineup

September 4, 2024
Kingston’s Best Products to Enhance Your Sibling Bond This Raksha Bandhan
Tech

Kingston’s Best Products to Enhance Your Sibling Bond This Raksha Bandhan

August 20, 2024
Next Post

Union Minister Dr Jitendra Singh lays the Foundation Stone of new Students' Hostels in the premises of the famous Cotton University

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

RECOMMENDED NEWS

Veteran actor Biswajit Chatterjee crowned as Indian Personality of the Year at IFFI 51 Closing Ceremony

4 years ago

Bhuj The Pride Of India showcases the war era of 1971 with life like sets, fighter jets and the biggest action sequences

4 years ago

Quickly separating black plastic packaging according to type

4 years ago

InsuranceDekho is keeping up the speed of business with an NPS of more than 90%

3 years ago
gintaa aims to be a market leader in the e-commerce sector with a robust buy sell exchange policy

gintaa aims to be a market leader in the e-commerce sector with a robust buy sell exchange policy

3 years ago

Lelomoz – Made in India Short Video App to earn money

3 years ago

BROWSE BY CATEGORIES

  • Agriculture
  • App News
  • Astrology
  • Auto
  • Business
  • Education
  • Entertainment
  • Fashion & Beauty
  • Finance/Money
  • Food
  • Gadgets
  • Health & Fitness
  • Lifestyle
  • National
  • Photography
  • Politics
  • Press Release
  • Religion
  • Science
  • Social Work
  • Sports
  • State News
  • Tech
  • Travel
  • Uncategorized
  • World

BROWSE BY TOPICS

Ace Entrepreneur actor Artificial intelligence Bengaluru Blockchain technology COVID-19 Cryptocurrency CSIR DBT Delhi Department of Biotechnology digital marketing DST Dubai Education entrepreneur Fairplay Gujarat Gurugram Hyderabad IIT Delhi Indian Institute of Technology Influencer Influencerquipo innovation Kingston Technology K Raheja Corp Homes LANXESS memory products and technology solutions model MoES Mumbai Music Industry producer Pune real estate research science Shan Se Entertainment Shantanu Bhamare Social Activist social media Surat technology solutions Urvashi Rautela

Latest News

Aveya IVF & Fertility Center: Pioneering Accessible Parenthood with Fertility Solutions

Aveya IVF & Fertility Center: Pioneering Accessible Parenthood with Fertility Solutions

May 14, 2025
The Rise of Skill-Based Learning: Redefining Education for the 21st Century

The Rise of Skill-Based Learning: Redefining Education for the 21st Century

May 14, 2025
Krishiyug Inovatives Pvt. Ltd.: Where Ancient Farming Wisdom Meets Rural Empowerment

Krishiyug Inovatives Pvt. Ltd.: Where Ancient Farming Wisdom Meets Rural Empowerment

May 14, 2025
Rice Over Bread: How Lenexis Foodworks Captured India’s Chinese Food Market

Rice Over Bread: How Lenexis Foodworks Captured India’s Chinese Food Market

May 14, 2025
Jahangir Tutorials: Bridging the Language Gap for South Indian Commerce Aspirants

Jahangir Tutorials: Bridging the Language Gap for South Indian Commerce Aspirants

May 13, 2025

Popular News

  • IIT Delhi launches new online platform to facilitate researchers

    59 shares
    Share 24 Tweet 15
  • Bonding well with your in-laws

    55 shares
    Share 22 Tweet 14
  • Decimal Point Analytics (DPA) with 400 candidates, targets for 4000-Mega job and Career Opportunities

    54 shares
    Share 22 Tweet 14
  • Euro Pratik set to revolutionise Indian interiors market

    53 shares
    Share 21 Tweet 13
  • Young Indian stunt performer winning heart of Dubai’s people – Narsimha Chouhan (Nattu)

    53 shares
    Share 21 Tweet 13
  • Creating waves in the online education sector, enter JOTOBOTO

    53 shares
    Share 21 Tweet 13
  • Jasmin Bhasin on the Cover Page of The Lifestyle Journalist Magazine

    52 shares
    Share 21 Tweet 13

Tribune Newsline, digital news and story platform bring you the news, articles, stories, and opinions on the latest happenings worldwide covering various sectors like nation, politics, and governance, social sector, review, foreign affairs, defence and security, latest review, lifestyle, entertainment, sports, technology, auto sectors, education, business and start-ups updates, Agriculture, Science, finance, money, food, and culture, etc.

Follow us on social media:

Latest News

  • Aveya IVF & Fertility Center: Pioneering Accessible Parenthood with Fertility Solutions
  • The Rise of Skill-Based Learning: Redefining Education for the 21st Century
  • Krishiyug Inovatives Pvt. Ltd.: Where Ancient Farming Wisdom Meets Rural Empowerment
  • Rice Over Bread: How Lenexis Foodworks Captured India’s Chinese Food Market
  • Jahangir Tutorials: Bridging the Language Gap for South Indian Commerce Aspirants
  • Pahia: A Mohali-Based Startup Empowering Street Vendors with Technology

Category

May 2025
M T W T F S S
 1234
567891011
12131415161718
19202122232425
262728293031  
« Apr    

Recent News

Aveya IVF & Fertility Center: Pioneering Accessible Parenthood with Fertility Solutions

Aveya IVF & Fertility Center: Pioneering Accessible Parenthood with Fertility Solutions

May 14, 2025
The Rise of Skill-Based Learning: Redefining Education for the 21st Century

The Rise of Skill-Based Learning: Redefining Education for the 21st Century

May 14, 2025
  • About Us
  • Advertise
  • Contact Us
  • DMCA
  • Follow on Google News

© 2022 Tribune Newsline.

No Result
View All Result
  • About Us
  • Advertise
  • Contact Us
  • DMCA
  • Home
  • Privacy Policy

© 2022 Tribune Newsline.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In